EVALUATION OF PROTEIN C, PROTEIN S AND FIBRINOGEN OF PREGNANT WOMEN WITH MALARIA IN OWERRI METROPOLIS

  • Emmanuel Ifeanyi Obeagu Department of Medical Laboratory Science, Madonna University Nigeria, Elele Campus, Rivers State, Nigeria
  • Getrude Uzoma Obeagu Department of Nursing Science, Ebonyi State University, Abakaliki, Ebonyi State, Nigeria.
  • Chidimma Maureen Chukwueze Department of Medical Laboratory Science, Enugu State University of Science and Technology, Enugu State, Nigeria.
  • Justina N. Ikpenwa Department of Guidance and counseling, Faculty of Education, Enugu State University of Science and Technology, Enugu State, Nigeria.
  • Gina Flor Ramos Department of Pharmacognosy, Faculty of Pharmacy, Madonna University Nigeria, Elele Campus, Rivers State, Nigeria.
Keywords: Protein C, Protein S, fibrinogen, Malaria, pregnant women

Abstract

This study was performed to evaluate protein C, protein S and fibrinogen levels in pregnant women with malaria in Owerri Metropolis. The study was carried out at the Owerri, Federal Medical Center in Imo, Nigeria. A total of 600 subjects from 1845 years of age were recruited for the study. The study included 300 pregnant women with malaria and 300 pregnant women without malaria who visited the Federal Health Center's Owerri, Maternity Hospital. Five milliliters (5 ml) of venous blood was obtained from each participant using standard venipuncture and placed in a simple serum collection container. The results showed an increase in protein C (P = 0.000), a decrease in fibrinogen (P = 0.000) and no significant difference in protein S (P = 0.309) in pregnant women with malaria compared with women with malaria. Pregnant women do not have malaria. This study showed that protein C increased, fibrinogen decreased, and protein S remained unchanged. Pregnant women with malaria studied may show changes in these regulatory clotting proteins.

Published
2022-04-19
How to Cite
Obeagu, E. I., Obeagu, G. U., Chukwueze, C. M., Ikpenwa, J. N., & Ramos, G. F. (2022). EVALUATION OF PROTEIN C, PROTEIN S AND FIBRINOGEN OF PREGNANT WOMEN WITH MALARIA IN OWERRI METROPOLIS. Madonna University Journal of Medicine and Health Sciences ISSN: 2814-3035, 2(2), 1-9. Retrieved from https://madonnauniversity.edu.ng/journals/index.php/medicine/article/view/58
Issue
Vol 2 No 2 (2022): MUJMHS
Section
Articles
Copyright (c) 2022 Madonna University journal of Medicine and Health Sciences ISSN: 2814-3035