EVALUATION OF PROTEIN C, PROTEIN S AND FIBRINOGEN OF PREGNANT WOMEN IN OWERRI METROPOLIS
Abstract
This study was performed to evaluate the levels of protein C, protein S and fibrinogen in pregnant women in the municipality of Owerri. The study was conducted at the Owerri Federal Medical Center in Imo, Nigeria. A total of 400 subjects from 1845 years of age were recruited for the study. The study included 300 pregnant women and 300 non-pregnant women who attended the Owerri Federal Medical Center Obstetrics and Gynecology Hospital. Five milliliters (5 ml) of venous blood was obtained from each participant using standard venipuncture and placed in a simple serum collection container. The results showed an increase in protein C (P= 0.015) and protein S (P = 0.014), with no significant difference in fibrinogen (P = 0.729) in pregnant women compared with non-pregnant women. .. Pregnancy has been shown to have an effect on protein C and protein S levels, but not on fibrinogen levels.