An Evaluation of the correlation between canities and T3 level, and age in female subjects
Abstract
Canities is the graying of hair. It is usually hereditary and a most dramatic change in hair, which finally ends as white hair. The pathogenesis is not yet clear though several hypotheses have been suggested. This study was aimed at establishing the relationship of canities with triiodothyronine (T3) level and age in female subjects. Eighty-eight (88) apparently healthy subjects aged eighteen (18) and above were used. Triiodothyronine level was determined using Enzyme Linked immunoabsorbent Assay (ELISA) as modified by Accubind ELISA microwell monobind Inc, lake Forest, CA 92630, USA. Data analysis were done using Fisher exact test, ANOVA, chi-square test and linear correlation coefficient by using SP statistical software 15.0 for windows 7 (SPSS Inc., Chicago, IL USA). Comparison of both Mean ± SD of subjects with canities and without canities revealed a statistically significant difference between canities and T3 level (p = 1.79E – 09). There was a positive significant correlation between canities and T3 level (r = 0.59). Also comparison the five groups according to those with canities and those without canities revealed that there was a statistically significant difference between age and having canities (p = 6.45E - 11).
