ANTISERA POTENTIAL OF INDIGENOUS NIGERIAN PLANT LECTINS: A REVIEW

  • Musa Abidemi MUHIBI
  • Busira Adesina TIJANI1
  • Mathew Folaranmi OLANIYAN1
  • Yekeen Adebisi KOSAMAT
  • Victor Olatunji MABAYOJE
  • Zaccheaus Awortu JEREMIAH
Keywords: Lectins, anti-sera agents, agglutination activity, indigenous plants, applications.

Abstract

Lectins are carbohydrate-binding proteins ubiquitous in nature, particularly abundant in plants. Indigenous Nigerian plants represent a vast untapped resource for novel lectins with diverse biological properties. This review explores the potential of these lectins as anti-sera agents. We will discuss the isolation, purification, and characterization of lectins from Nigerian plants. Additionally, we will explore the in vitro and in vivo studies evaluating their agglutination activity against various blood types. The review will highlight the advantages of utilizing indigenous lectins for therapeutic applications due to their potential specificity and reduced immunogenicity. Finally, we will address the challenges and future directions for research in this field, emphasizing the need for further exploration and development of these promising anti-sera agents from Nigeria's rich botanical heritage.

Author Biographies

Musa Abidemi MUHIBI

Department of Medical Laboratory Science, Faculty of Applied Health Sciences, Edo State University, Uzairue, Edo State, Nigeria

Busira Adesina TIJANI1

Department of Medical Laboratory Science, Faculty of Applied Health Sciences, Edo State University, Uzairue, Edo State, Nigeria

Mathew Folaranmi OLANIYAN1

Department of Medical Laboratory Science, Faculty of Applied Health Sciences, Edo State University, Uzairue, Edo State, Nigeria

Yekeen Adebisi KOSAMAT

Department of Medical Laboratory Science, Faculty of Basic Medical Sciences, Osun State University, Osogbo, Osun State, Nigeria.

Victor Olatunji MABAYOJE

Department of Haematology and Blood Transfusion Science, Faculty of Basic Clinical Science, Osun State University, Osogbo, Osun State, Nigeria.

Zaccheaus Awortu JEREMIAH

Department of Haematology and Blood Transfusion Science, Faculty of Medical Laboratory Science, Rivers State University, Port Harcourt,Nigeria.

Published
2024-07-25
How to Cite
MUHIBI, M. A., TIJANI1B. A., OLANIYAN1M. F., KOSAMAT, Y. A., MABAYOJE, V. O., & JEREMIAH, Z. A. (2024). ANTISERA POTENTIAL OF INDIGENOUS NIGERIAN PLANT LECTINS: A REVIEW. Madonna University Journal of Medicine and Health Sciences ISSN: 2814-3035, 4(1), 9. Retrieved from https://madonnauniversity.edu.ng/journals/index.php/medicine/article/view/162
Section
Articles